Description

8-Bromo-2-Methylisoquinolin-1(2H)-One is a high-purity brominated isoquinolinone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized heterocyclic core essential for constructing complex molecules with targeted biological or material properties. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for drug discovery and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Research: Used in the synthesis of new generation herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or functional additive in the development of advanced organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific compounds.
• Academic & Institutional Research: Employed in university and government laboratories for methodological development and exploratory synthesis projects.

Basic Information

Product Name	8-Bromo-2-Methylisoquinolin-1(2H)-One
CAS No.	643069-17-4
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	8-Bromo-2-methyl-1,2-dihydroisoquinolin-1-one; 8-Bromo-2-methyl-1H-isoquinolin-1-one; 1(2H)-Isoquinolinone, 8-bromo-2-methyl-; 2-Methyl-8-bromo-1,2-dihydroisoquinolin-1-one; 8-Bromo-2-methylisoquinolin-1-ol (tautomer); 8-Bromo-2-methyl-1-isoquinolone
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-Methylisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.