Description

1H-Pyrrolo[1,2-C]Imidazole-1,3(2H)-Dione,Tetrahydro-2-(2-Propynyl)-,(7As)-(9Ci) CAS NO 642460-52-4 is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in cutting-edge drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for constructing novel heterocyclic scaffolds with potential biological activity.
• Research & Development (R&D): Employed in academic and industrial labs for method development and exploring new chemical entities (NCEs).
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1H-Pyrrolo[1,2-C]Imidazole-1,3(2H)-Dione,Tetrahydro-2-(2-Propynyl)-,(7As)-(9Ci)
CAS No.	642460-52-4
Molecular Formula	C9H10N2O2
Molecular Weight	178.19 g/mol
Synonyms	(7aS)-Tetrahydro-2-(prop-2-yn-1-yl)-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione; Tetrahydro-2-(2-propynyl)-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione, (7aS)-; 642460-52-4; (7aS)-2-(Prop-2-yn-1-yl)hexahydro-1H-pyrrolo[1,2-c]imidazole-1,3-dione
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity suitable for pharmaceutical research. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as assay, identity, and impurity profiles. We support development under quality agreements and can align with GMP guidelines for non-clinical and clinical stage materials upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.