Description

4-Oxo-6-(Trifluoromethyl)-1,4-Dihydroquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its quinoline carboxylic acid core and trifluoromethyl substituent. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. It is primarily sought by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of anti-infective and anti-inflammatory agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinolone and fluoroquinolone-based APIs.
• Anti-infective Drug Research: Used in R&D for developing next-generation antibacterial and antiviral compounds.
• Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds in medicinal chemistry.
• Biochemical Research: Employed in studies targeting enzyme inhibition and receptor binding assays.
• Material Science: Potential use in the development of organic electronic materials due to its conjugated structure.

Basic Information

Product Name	4-Oxo-6-(Trifluoromethyl)-1,4-Dihydroquinoline-3-Carboxylic Acid
CAS No.	641993-21-7
Molecular Formula	C11H6F3NO3
Molecular Weight	257.17 g/mol
Synonyms	6-(Trifluoromethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 6-Trifluoromethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1,4-Dihydro-6-(trifluoromethyl)-4-oxoquinoline-3-carboxylic acid; 4-Hydroxy-6-(trifluoromethyl)quinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 1,4-dihydro-6-(trifluoromethyl)-4-oxo-; 641993-21-7; 6-Trifluoromethyl-4-hydroxyquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-Oxo-6-(Trifluoromethyl)-1,4-Dihydroquinoline-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and tested in facilities operating under cGMP principles. Certificates of Analysis (COA) are provided with each shipment, detailing purity, identity, and impurity profiles as confirmed by HPLC, NMR, and mass spectrometry. We support compliance with global regulatory standards including ICH guidelines and REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.