Description

5-Chloro-4-Hydroxy-8-Methoxyquinoline-3-Carboxylic Acid is a high-purity, synthetically versatile quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and functionalized structure makes it an indispensable intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for its role in creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Research: Used in developing advanced fungicides and herbicides, leveraging its bioactive quinoline core.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and organic electronic materials.
• Chemical Synthesis: An essential building block for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Analytical Reference Standard: Employed as a high-purity standard in quality control (QC) and research & development (R&D) laboratories for method development and validation.

Basic Information

Product Name	5-Chloro-4-Hydroxy-8-Methoxyquinoline-3-Carboxylic Acid
CAS No.	641993-16-0
Molecular Formula	C₁₁H₈ClNO₄
Molecular Weight	253.64 g/mol
Synonyms	5-Chloro-4-hydroxy-8-methoxyquinoline-3-carboxylic acid; 8-Methoxy-5-chloro-4-hydroxyquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 5-chloro-4-hydroxy-8-methoxy-; 5-Chloro-4-hydroxy-8-methoxy-3-quinolinecarboxylic acid; 641993-16-0; 5-Chloro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Hydroxy-8-Methoxyquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.