Description

2-(4-Bromophenyl)-6-Fluoro-4-Hydroxymethyl-3-Methylquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its complex quinoline-based structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. Research and development teams in the global pharmaceutical and agrochemical industries need this precise chemical for developing next-generation drugs and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging its halogenated quinoline core.
• Material Science: Acts as a monomer or functional additive in the research of advanced organic electronic materials, such as OLEDs and sensors.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities, government labs, and CROs (Contract Research Organizations) for structure-activity relationship (SAR) studies.
• Fluorescent Probe Synthesis: Utilized in the design and synthesis of fluorescent markers and probes for biochemical and diagnostic applications.
• Catalyst Ligand Development: Investigated as a potential ligand for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	2-(4-Bromophenyl)-6-Fluoro-4-Hydroxymethyl-3-Methylquinoline
CAS No.	641611-78-1
Molecular Formula	C18H15BrFNO
Molecular Weight	360.22 g/mol
Synonyms	6-Fluoro-4-(hydroxymethyl)-3-methyl-2-(4-bromophenyl)quinoline; 2-(4-Bromophenyl)-6-fluoro-3-methyl-4-quinolinemethanol; 4-(Hydroxymethyl)-6-fluoro-3-methyl-2-(4-bromophenyl)quinoline; Quinoline, 2-(4-bromophenyl)-6-fluoro-4-(hydroxymethyl)-3-methyl-; 641611-78-1; 2-(p-Bromophenyl)-6-fluoro-4-hydroxymethyl-3-methylquinoline
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-6-Fluoro-4-Hydroxymethyl-3-Methylquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants. For long-term storage, consider an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.