Description

4(1H)-Quinazolinone, 6,7,8-Trimethoxy-2-(Trifluoromethyl)- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinazolinone core and trifluoromethyl substituent. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for creating novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of potential drug candidates, particularly in oncology and CNS therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: The quinazolinone structure is a privileged motif in the design of kinase inhibitors for potential cancer therapies.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Utilized in advanced organic synthesis for introducing the trifluoromethylated quinazolinone moiety into more complex molecular architectures.

Basic Information

Item	Detail
Product Name	4(1H)-Quinazolinone, 6,7,8-Trimethoxy-2-(Trifluoromethyl)- (9Ci)
CAS No.	640297-56-9
Molecular Formula	C₁₂H₁₁F₃N₂O₄
Molecular Weight	304.22 g/mol
Synonyms	6,7,8-Trimethoxy-2-(trifluoromethyl)quinazolin-4(1H)-one; 2-(Trifluoromethyl)-6,7,8-trimethoxy-4(1H)-quinazolinone; 4(1H)-Quinazolinone, 6,7,8-trimethoxy-2-(trifluoromethyl)-; 640297-56-9; 6,7,8-Trimethoxy-2-trifluoromethyl-4(1H)-quinazolinone
EINECS	Contact for details

Quality Control

Every batch of our 4(1H)-Quinazolinone, 6,7,8-Trimethoxy-2-(Trifluoromethyl)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.