Description

2(1H)-Quinolinone, 1-Acetyl- is a specialized heterocyclic organic compound belonging to the quinolinone class, serving as a valuable building block in advanced chemical synthesis. Its acetyl-substituted quinolinone core makes it a critical intermediate for developing novel pharmaceuticals and functional materials. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in therapeutic areas targeting neurological and inflammatory pathways.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides due to its bioactive quinolinone structure.
• Material Science Research: Serves as a precursor for organic light-emitting diodes (OLEDs) and other electronic materials requiring specific photophysical properties.
• Chemical Research & Development: Employed as a versatile building block in organic synthesis for constructing complex heterocyclic frameworks in academic and industrial labs.
• Ligand and Catalyst Development: Utilized in the design of novel ligands for metal catalysis and coordination chemistry applications.

Basic Information

Product Name	2(1H)-Quinolinone, 1-Acetyl-
CAS No.	639463-87-9
Molecular Formula	C11H9NO2
Molecular Weight	187.20 g/mol
Synonyms	1-Acetyl-2(1H)-quinolinone; 1-Acetylquinolin-2(1H)-one; N-Acetyl-2-quinolone; 1-Acetyl-1H-quinolin-2-one; 2-Quinolone, 1-acetyl-; 1-Acetyl-2-quinolone; 1-Acetyl-2-hydroxyquinoline; N-Acetyl-2(1H)-quinolinone
EINECS	Contact for details

Quality Control

Our 2(1H)-Quinolinone, 1-Acetyl- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry. Our quality assurance protocols are designed to meet the stringent requirements of cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.