Description

2H-1-Benzopyran-3,4-Diol, 3,4-Dihydro-6-Methoxy-2,2-Dimethyl-, (3R,4R)- (9Ci) is a high-purity, stereochemically defined chroman derivative, a key chiral building block in advanced organic synthesis. Its precise (3R,4R) configuration makes it a valuable intermediate for the development of enantiomerically pure pharmaceuticals and bioactive compounds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate complex chroman motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon for the synthesis of potential drug candidates, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of novel, optically active pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Fine Chemical Synthesis: Acts as a versatile precursor for the preparation of complex natural product analogs and specialty chemicals.
• Asymmetric Catalysis Studies: Employed as a standard or ligand precursor in research focused on developing new stereoselective synthetic methodologies.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies due to its diol functionality and rigid benzopyran structure.

Basic Information

Product Name	2H-1-Benzopyran-3,4-Diol, 3,4-Dihydro-6-Methoxy-2,2-Dimethyl-, (3R,4R)- (9Ci)
CAS No.	639092-19-6
Molecular Formula	C₁₂H₁₆O₄
Molecular Weight	224.25 g/mol
Synonyms	(3R,4R)-3,4-Dihydro-6-methoxy-2,2-dimethyl-2H-1-benzopyran-3,4-diol; (3R,4R)-6-Methoxy-2,2-dimethylchroman-3,4-diol; (3R,4R)-Dihydro-6-methoxy-2,2-dimethyl-2H-1-benzopyran-3,4-diol; (3R,4R)-Chromane-3,4-diol, 6-methoxy-2,2-dimethyl-; 2H-1-Benzopyran-3,4-diol, 3,4-dihydro-6-methoxy-2,2-dimethyl-, (3R,4R)-; (3R,4R)-6-Methoxy-2,2-dimethyl-3,4-dihydro-2H-chromene-3,4-diol
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-3,4-Diol, 3,4-Dihydro-6-Methoxy-2,2-Dimethyl-, (3R,4R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for research and development. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.