Description

2,1-Benzisoxazole, 3-Fluoro-1,3-Dihydro-1-Hydroxy- (9Ci) is a specialized fluorinated benzisoxazole derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fused-ring structure and fluorine substituent enable precise modulation of biological activity and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to innovate and scale new molecular entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy and environmental profile.
• Fine Chemical Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Material Science Research: Potential intermediate for developing specialty polymers, liquid crystals, or organic electronic materials due to its rigid benzisoxazole core.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial manufacturing of high-value specialty chemicals.

Basic Information

Product Name	2,1-Benzisoxazole, 3-Fluoro-1,3-Dihydro-1-Hydroxy- (9Ci)
CAS No.	639030-19-6
Molecular Formula	C7H4FNO2
Molecular Weight	153.11 g/mol
Synonyms	3-Fluoro-1-hydroxy-1,3-dihydro-2,1-benzisoxazole; 1-Hydroxy-3-fluoro-1,3-dihydro-2,1-benzisoxazole; 3-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzisoxazole; 2,1-Benzisoxazole, 3-fluoro-1,3-dihydro-1-hydroxy-; Fluorinated benzisoxazole alcohol; 3-Fluoro-1H-2,1-benzisoxazol-1-ol; 639030-19-6
EINECS	Contact for details

Quality Control

Our 2,1-Benzisoxazole, 3-Fluoro-1,3-Dihydro-1-Hydroxy- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.