Description

6-Bromo-2-[5-(2-Chlorophenyl)Furan-2-Yl]Quinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 637323-38-7. This compound is valued for its role as a critical building block in the synthesis of novel, small-molecule drug candidates, particularly in oncology and anti-inflammatory research. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted therapeutic agents, especially kinase inhibitors and other biologically active heterocyclic compounds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates with improved efficacy and safety profiles.
• Process Chemistry & Scale-up: Serves as a critical raw material for process research and development (PR&D) and the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed as a tool compound or a scaffold for probing biological pathways and protein-ligand interactions in academic and industrial R&D settings.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex, high-value specialty chemicals for various advanced material applications.

Basic Information

Product Name	6-Bromo-2-[5-(2-Chlorophenyl)Furan-2-Yl]Quinoline-4-Carboxylic Acid
CAS No.	637323-38-7
Molecular Formula	C20H11BrClNO3
Molecular Weight	428.66 g/mol
Synonyms	6-Bromo-2-[5-(2-chlorophenyl)-2-furanyl]-4-quinolinecarboxylic acid; 6-Bromo-2-(5-(2-chlorophenyl)furan-2-yl)quinoline-4-carboxylic acid; Quinoline-4-carboxylic acid, 6-bromo-2-[5-(2-chlorophenyl)-2-furanyl]-; 637323-38-7; 6-Br-2-(5-(2-Cl-Ph)-Fur-2-yl)-Quin-4-COOH
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-2-[5-(2-Chlorophenyl)Furan-2-Yl]Quinoline-4-Carboxylic Acid adheres to stringent quality management systems to ensure batch-to-batch consistency and purity suitable for advanced research and development. Every lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.