Description

1-(4-Fluoro-Phenyl)-4-Hydroxy-1H-Pyrazole-3-Carboxylic Acid Ethyl Ester is a high-purity fluorinated pyrazole derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Chemical Research & Development: Serves as a versatile precursor for heterocyclic chemistry, enabling the creation of libraries of compounds for high-throughput screening and lead optimization.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, ligands for catalysis, and organic electronic materials due to its functionalized pyrazole core.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-4-Hydroxy-1H-Pyrazole-3-Carboxylic Acid Ethyl Ester
CAS No.	636568-08-6
Molecular Formula	C12H11FN2O3
Molecular Weight	250.23 g/mol
Synonyms	Ethyl 1-(4-fluorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylate; 4-Hydroxy-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid ethyl ester; 1-(4-Fluorophenyl)-4-hydroxypyrazole-3-carboxylic acid ethyl ester; 636568-08-6; 1H-Pyrazole-3-carboxylic acid, 1-(4-fluorophenyl)-4-hydroxy-, ethyl ester; 4-Hydroxy-1-(p-fluorophenyl)-1H-pyrazole-3-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-Phenyl)-4-Hydroxy-1H-Pyrazole-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.