Description

4-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzoic Acid is a high-value, fluorinated aromatic compound that serves as a critical synthetic intermediate in advanced chemical manufacturing. Its molecular structure, featuring a trifluoromethylbenzyloxy substituent on a benzoic acid core, provides unique electronic and steric properties essential for developing specialized materials and active ingredients. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for applications in drug discovery, crop protection, and polymer synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced organic electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated into polymer chains to impart specific properties such as increased chemical resistance, altered solubility, or enhanced thermal stability.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating complex molecular architectures.
• Coordination Chemistry: Can act as a ligand or precursor for metal-organic frameworks (MOFs) and other coordination complexes.

Basic Information

Product Name	4-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzoic Acid
CAS No.	632366-16-6
Molecular Formula	C15H11F3O3
Molecular Weight	296.24 g/mol
Synonyms	4-[(3-(Trifluoromethyl)benzyl)oxy]benzoic acid; Benzoic acid, 4-[[[3-(trifluoromethyl)phenyl]methyl]oxy]-; 4-(3-Trifluoromethylbenzyloxy)benzoic Acid; 4-((3-(Trifluoromethyl)benzyl)oxy)benzoic Acid; 4-Hydroxybenzoic acid 3-(trifluoromethyl)benzyl ether; α,α,α-Trifluoro-m-tolyl 4-carboxyphenyl ether
EINECS	Contact for details

Quality Control

Our production of 4-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and relevant industry guidelines for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.