Description

Cobalt, Chloro[2,2'-[(1S,2S)-1,2-Cyclohexanediylbis[(Nitrilo-κn)Methylidyne]]Bis[4,6-Bis(1,1-Dimethylethyl)Phenolato-κo]]-, (Sp-5-13)- is a sophisticated, chiral organometallic complex designed for advanced catalytic applications. This compound matters for its role as a highly selective and efficient catalyst in asymmetric synthesis, enabling the production of enantiomerically pure intermediates critical to modern pharmaceuticals and fine chemicals. Industries such as pharmaceutical R&D, specialty chemical manufacturing, and advanced materials science rely on this precise catalyst to achieve superior reaction outcomes.

Application

• Asymmetric Catalysis: A key catalyst for enantioselective C-H activation, cyclopropanation, and other carbon-carbon bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Used in the production of chiral active pharmaceutical ingredients (APIs) and complex drug candidates.
• Fine Chemical Manufacturing: Enables the synthesis of high-value, optically pure flavors, fragrances, and agrochemical intermediates.
• Polymer Science: Employed in the development of stereoregular polymers and advanced polymeric materials with specific chiral properties.
• Academic & Industrial Research: A valuable tool for methodology development in organic and organometallic chemistry laboratories.
• Ligand Screening & Catalyst Development: Serves as a benchmark or precursor complex in the discovery of new catalytic systems.

Basic Information

Product Name	Cobalt, Chloro[2,2'-[(1S,2S)-1,2-Cyclohexanediylbis[(Nitrilo-κn)Methylidyne]]Bis[4,6-Bis(1,1-Dimethylethyl)Phenolato-κo]]-, (Sp-5-13)-
CAS No.	630404-46-5
Molecular Formula	C38H56ClCoN2O2
Molecular Weight	667.22 g/mol
Synonyms	(Sp-5-13)-Chloro[(1S,2S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminato]cobalt(III); Cobalt(III) salen complex (chiral, chloro derivative); (S,S)-Chloro(N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino)cobalt; Jacobsen-type cobalt catalyst; Chiral cobalt salen complex; Co(salen)Cl derivative; Asymmetric cobalt catalyst; Cobalt-Schiff base complex. Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of our chiral cobalt catalyst is produced and tested under strict quality management protocols to ensure consistent performance and purity. We provide comprehensive Certificates of Analysis (COA) detailing chiral purity, metal content, and impurity profiles. Our quality systems support compliance with cGMP standards for pharmaceutical applications, and we welcome audits and custom specification development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or light should be avoided to maintain catalytic activity and purity.

Specification

Item	Specification
Appearance	Dark green to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Assay (Cobalt Content)	8.5 - 9.0 %
Loss on Drying	≤ 0.5 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.