Description

1H-Indene-4-Carboxylicacid,Octahydro-7-Oxo-,Methylester,(3As,4S,7As)-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise control over the final product's three-dimensional structure. Pharmaceutical R&D and fine chemical synthesis teams need it for developing new therapeutic agents, particularly in areas requiring chiral specificity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in complex multi-step syntheses, including cyclization and functional group transformation reactions.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in studies exploring new catalytic methodologies.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Academic & Industrial R&D: A valuable reagent for universities and corporate research labs focusing on synthetic organic chemistry.

Basic Information

Item	Detail
Product Name	1H-Indene-4-Carboxylicacid,Octahydro-7-Oxo-,Methylester,(3As,4S,7As)-(9Ci)
CAS No.	630103-79-6
Molecular Formula	C12H18O3
Molecular Weight	210.27 g/mol
Synonyms	(3aS,4S,7aS)-Octahydro-7-oxo-1H-indene-4-carboxylic acid methyl ester; Methyl (3aS,4S,7aS)-octahydro-7-oxo-1H-indene-4-carboxylate; 1H-Indene-4-carboxylic acid, octahydro-7-oxo-, methyl ester, (3aS,4S,7aS)-; (4S,3aS,7aS)-Methyl octahydro-7-oxo-1H-indene-4-carboxylate; Chiral indanone derivative ester; Advanced chiral synthon
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques, including HPLC, GC, and chiral analysis, to guarantee identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing lot-specific results are available upon request. Our quality management system supports development under GMP-like conditions for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.