Description

5-Bromo-4-Fluoro-2-Methylaniline is a high-purity halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the bromo and fluoro substituents enhance biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: An excellent substrate for Buchwald-Hartwig amination, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom.

Basic Information

Product Name	5-Bromo-4-Fluoro-2-Methylaniline
CAS No.	627871-16-3
Molecular Formula	C7H7BrFN
Molecular Weight	204.04 g/mol
Synonyms	2-Amino-5-bromo-4-fluoro-1-methylbenzene; 2-Methyl-5-bromo-4-fluoroaniline; 5-Bromo-4-fluoro-o-toluidine; 4-Fluoro-5-bromo-2-methylaniline; Benzenamine, 5-bromo-4-fluoro-2-methyl-; 627871-16-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoro-2-Methylaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.