Description

2-Bromo-7-Fluoronaphthalene is a halogenated naphthalene derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both bromine and fluorine substituents, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport materials and host molecules in display and lighting technologies.
• Liquid Crystal & Polymer Chemistry: Employed in the synthesis of fluorinated monomers and mesogens to modify the thermal and optical properties of advanced polymers and liquid crystal displays (LCDs).
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to create biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluorochemistry and heterocyclic compound synthesis.

Basic Information

Product Name	2-Bromo-7-Fluoronaphthalene
CAS No.	627527-30-4
Molecular Formula	C₁₀H₆BrF
Molecular Weight	225.06 g/mol
Synonyms	7-Fluoro-2-bromonaphthalene; 2-Bromo-7-fluoronaphthalene; Naphthalene, 2-bromo-7-fluoro-; 2-Brom-7-fluornaphthalin; 2-Bromo-7-fluoro-naphthalene; 627527-30-4; 2-Br-7-F-Naphthalene
EINECS	Contact for details

Quality Control

Our 2-Bromo-7-Fluoronaphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.