Description

tert-Butyl 3-Hydroxy-7,8-Dihydro-1,6-Naphthyridine-6(5H)-Carboxylate is a high-value, protected heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of complex pharmaceutical molecules, offering a versatile scaffold for medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, particularly in therapeutic areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to create complex fused heterocyclic systems.
• Chemical Biology Probes: Useful in the development of molecular probes for studying biological pathways and target engagement.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and herbicides.

Basic Information

Product Name	tert-Butyl 3-Hydroxy-7,8-Dihydro-1,6-Naphthyridine-6(5H)-Carboxylate
CAS No.	625098-86-4
Molecular Formula	C₁₃H₁₈N₂O₃
Molecular Weight	250.29 g/mol
Synonyms	6-(tert-Butoxycarbonyl)-3-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine; 3-Hydroxy-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylic acid tert-butyl ester; tert-Butyl 3-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate; Boc-Protected 3-Hydroxy-1,6-naphthyridine; 1,6-Naphthyridine-6(5H)-carboxylic acid, 7,8-dihydro-3-hydroxy-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Hydroxy-7,8-Dihydro-1,6-Naphthyridine-6(5H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your research and development needs with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.