Description

(S,E)-2-Methyl-n-Propylidenepropane-2-Sulfinamide is a high-purity chiral sulfinamide building block, a critical intermediate in modern asymmetric synthesis. Its primary value lies in its ability to act as a highly effective chiral auxiliary or ligand, enabling the stereoselective construction of complex molecules with high enantiomeric purity. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• As a versatile chiral auxiliary in the asymmetric synthesis of amines, amino acids, and other nitrogen-containing compounds.
• As a key ligand precursor for the development of transition metal catalysts used in enantioselective reactions.
• In the research and development of pharmaceutical intermediates for novel therapeutic agents.
• For the synthesis of agrochemical intermediates requiring specific stereochemistry for enhanced activity.
• In academic and industrial R&D for methodological studies in organic and medicinal chemistry.
• As a building block for custom synthesis and contract manufacturing of complex chiral molecules.

Basic Information

Product Name	(S,E)-2-Methyl-n-Propylidenepropane-2-Sulfinamide
CAS No.	623169-00-6
Molecular Formula	C7H15NOS
Molecular Weight	161.26 g/mol
Synonyms	(S,E)-2-Methyl-1-(propylidene)propane-2-sulfinamide; (S,E)-2-Methyl-N-(propylidene)propane-2-sulfinamide; (S,E)-tert-Butanesulfinamide Propylidene Derivative; (S,E)-N-((E)-But-1-en-1-yl)-2-methylpropane-2-sulfinamide; (S,E)-N-(1-Butenylidene)-2-methyl-2-propanesulfinamide; (S,E)-2-Methyl-2-propanesulfinamide, N-(1-butenylidene)-, (S,E)-; Chiral Sulfinamide Auxiliary CAS 623169-00-6
EINECS	Contact for details

Quality Control

Our (S,E)-2-Methyl-n-Propylidenepropane-2-Sulfinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC/MS, to ensure high chemical and enantiomeric purity suitable for sensitive asymmetric synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.