Description

1-Thia-4,8-Diazaspiro[4.5]Decan-3-One,2-Ethyl-8-Methyl-,1-Oxide,(2S)-(9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and sulfoxide-containing structure. This compound is of significant value in modern medicinal chemistry for the research and development of novel therapeutic agents, particularly those targeting the central nervous system. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique spirocyclic scaffold.
• Protease Inhibitor Development: Serves as a core structural motif in the design of novel enzyme inhibitors.
• Ligand Synthesis for Receptor Targeting: Employed in creating sophisticated ligands for G-protein-coupled receptors (GPCRs) and other biological targets.
• Asymmetric Synthesis: Utilized in chiral synthesis processes, leveraging its defined (2S) stereochemistry.
• Chemical Biology Probes: Acts as a precursor for developing molecular probes to study biological pathways.

Basic Information

Product Name	1-Thia-4,8-Diazaspiro[4.5]Decan-3-One,2-Ethyl-8-Methyl-,1-Oxide,(2S)-(9Ci)
CAS No.	623168-05-8
Molecular Formula	C9H16N2O2S
Molecular Weight	216.30 g/mol
Synonyms	(2S)-2-Ethyl-8-methyl-1-thia-4,8-diazaspiro[4.5]decan-3-one 1-oxide; 2-Ethyl-8-methyl-1-thia-4,8-diazaspiro[4.5]decan-3-one 1-oxide, (2S)-; (2S)-2-Ethyl-8-methyl-1,1-dioxo-1-thia-4,8-diazaspiro[4.5]decan-3-one; 1-Thia-4,8-diazaspiro[4.5]decan-3-one, 2-ethyl-8-methyl-, 1-oxide, (2S)-; Spirocyclic sulfoxide intermediate; (2S)-2-Ethyl-8-methyl-1-oxido-1-thia-4,8-diazaspiro[4.5]decan-3-one
EINECS	Contact for details

Quality Control

Our 1-Thia-4,8-Diazaspiro[4.5]Decan-3-One,2-Ethyl-8-Methyl-,1-Oxide,(2S)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.