Description

7-Fluoro-1,4-Dihydro-6-Methoxy-4-Oxoquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the quinoline carboxylic acid class. This compound is of critical importance for its role as a key building block in the synthesis of novel fluoroquinolone antibiotics and other active pharmaceutical ingredients (APIs). It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development and production of next-generation antibacterial agents and specialty organic molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of advanced fluoroquinolone antibiotic candidates, enabling the introduction of the 7-fluoro and 6-methoxy substituents critical for antibacterial activity and spectrum.
• Antibacterial Drug Research: Serves as a core scaffold in medicinal chemistry for designing and testing new antibacterial agents targeting DNA gyrase and topoisomerase IV enzymes.
• Fine Chemical Synthesis: Used in the preparation of complex quinoline-based derivatives for various applications in agrochemicals and material science research.
• Reference Standard: Employed as an analytical standard in quality control laboratories for the identification and quantification of related substances in API manufacturing.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	7-Fluoro-1,4-Dihydro-6-Methoxy-4-Oxoquinoline-3-Carboxylic Acid
CAS No.	622369-36-2
Molecular Formula	C11H8FNO4
Molecular Weight	237.19 g/mol
Synonyms	6-Methoxy-7-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 7-Fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 1,4-dihydro-7-fluoro-6-methoxy-4-oxo-; 7-Fluoro-6-methoxy-4-oxoquinoline-3-carboxylic acid; 1,4-Dihydro-7-fluoro-6-methoxy-4-oxo-3-quinolinecarboxylic acid; CAS 622369-36-2
EINECS	Contact for details

Quality Control

Our 7-Fluoro-1,4-Dihydro-6-Methoxy-4-Oxoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance assurance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.