Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-(4-Methoxybenzoyl)-1-Piperazinyl]-4-Oxo- is a high-purity advanced pharmaceutical intermediate (API intermediate) with a complex heterocyclic structure. This compound is of critical importance for its role in the synthesis of novel fluoroquinolone antibiotics and other active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and bulk API producers engaged in the development of next-generation antibacterial agents.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a crucial building block in the synthesis of advanced, broad-spectrum antibacterial agents.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and optimization of new therapeutic compounds targeting bacterial infections.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up production of final drug substances under current Good Manufacturing Practices (cGMP).
• Contract Synthesis and Custom Manufacturing: Supplied to CROs and CMOs for client-specific drug development projects.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Item	Detail
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-(4-Methoxybenzoyl)-1-Piperazinyl]-4-Oxo-
CAS No.	620170-31-2
Molecular Formula	C25H24FN3O4
Molecular Weight	449.48 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[4-(4-methoxybenzoyl)-1-piperazinyl]-4-oxo-3-quinolinecarboxylic acid; 7-[4-(4-Methoxybenzoyl)-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; Garenoxacin Intermediate; Garenoxacin Related Compound; AM-1155 Intermediate; OPC-17116 Intermediate; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[4-(4-methoxybenzoyl)-1-piperazinyl]-4-oxo-
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, identification by spectroscopic methods (IR, NMR), and control of specified impurities. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to ensure traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and under an inert atmosphere if necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.