Description

o-[Bis(4-Methoxyphenyl)Phosphinyl]-n-(tert-Butoxycarbonyl)Hydroxylamine is a specialized organophosphorus compound featuring a protected hydroxylamine group, making it a valuable synthetic intermediate. This compound is engineered to facilitate the controlled introduction of nitrogen and phosphorus functionalities in complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthesis and medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring phosphinyl or protected hydroxylamine motifs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Synthesis: Intermediate in the development of advanced herbicides, insecticides, or plant growth regulators containing phosphorus.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and metal complexation.
• Peptide & Protein Modification: Potential use in the site-specific modification of biomolecules through its reactive functional groups.
• Polymer Chemistry: Can be incorporated as a functional monomer or cross-linking agent in specialty polymer synthesis.

Basic Information

Product Name	o-[Bis(4-Methoxyphenyl)Phosphinyl]-n-(tert-Butoxycarbonyl)Hydroxylamine
CAS No.	619333-95-8
Molecular Formula	C20H26NO6P
Molecular Weight	407.40 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-O-[bis(4-methoxyphenyl)phosphinyl]hydroxylamine; BocNHOP(O)(C6H4OCH3-p)2; tert-Butyl N-[bis(4-methoxyphenyl)phosphoryloxy]carbamate; O-(Di-p-anisylphosphinyl)-N-Boc-hydroxylamine; (Boc-NH-O-P(O)(4-MeOC6H4)2); Protected Phosphinylhydroxylamine Derivative
EINECS	Contact for details

Quality Control

Every batch of o-[Bis(4-Methoxyphenyl)Phosphinyl]-n-(tert-Butoxycarbonyl)Hydroxylamine is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.