Description

D-Norvaline, Methyl Ester (Hydrochloride)(1:1) is a high-purity, non-proteinogenic amino acid derivative. This chiral building block is critical for the synthesis of complex peptides and pharmaceutical intermediates where stereochemical integrity is paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce the D-norvaline residue, influencing peptide conformation and stability.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway research.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in the preparation of enantiomerically pure compounds.
• Proteomics & Diagnostics: Can be used in the development of specialized reagents and markers for analytical applications.

Basic Information

Product Name	D-Norvaline, Methyl Ester (Hydrochloride)(1:1)
CAS No.	619330-91-5
Molecular Formula	C6H14ClNO2
Molecular Weight	167.63 g/mol
Synonyms	Methyl (2R)-2-amino-pentanoate hydrochloride; D-2-Aminopentanoic acid methyl ester hydrochloride; (R)-2-Aminopentanoic acid methyl ester hydrochloride; Methyl D-norvalinate hydrochloride; D-Norvaline methyl ester HCl; (R)-Norvaline methyl ester hydrochloride; Norvaline, D-, methyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our D-Norvaline, Methyl Ester (Hydrochloride)(1:1) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.