Description

2-Propenoic Acid, 3-[4-[[(2-Hydroxyethyl)[2-(1H-Indol-3-Yl)Ethyl]Amino]Methyl]Phenyl]-, Methyl Ester, (2E)- is a sophisticated acrylate derivative featuring an indole moiety, designed for advanced material synthesis and pharmaceutical research. This compound matters for its unique molecular architecture, which combines photoreactive and electron-donating properties, enabling the development of specialized functional polymers and bioactive conjugates. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, advanced material science, and specialty chemical sectors seeking to create novel photoresists, drug delivery systems, or liquid crystal materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting neurological pathways or requiring photodynamic therapy activation.
• Advanced Polymer Synthesis: Used as a functional monomer for creating specialty acrylate polymers with tailored properties like light responsiveness, adhesion, or specific biocompatibility.
• Photoresist & Imaging Materials: Incorporated into formulations for high-resolution photoresists used in microelectronics and advanced lithography due to its photoreactive acrylate group.
• Liquid Crystal & OLED Materials: Acts as a precursor or dopant in the development of organic light-emitting diodes (OLEDs) and liquid crystal displays (LCDs) to modify electronic or alignment properties.
• Bioconjugation & Probe Development: Utilized in life sciences for labeling biomolecules (proteins, antibodies) or creating fluorescent probes, leveraging the indole group's affinity for specific interactions.
• Specialty Coatings & Adhesives: Enhances the performance of high-end coatings and adhesives by imparting improved UV stability, cross-linking density, or substrate adhesion.

Basic Information

Item	Details
Product Name	2-Propenoic Acid, 3-[4-[[(2-Hydroxyethyl)[2-(1H-Indol-3-Yl)Ethyl]Amino]Methyl]Phenyl]-, Methyl Ester, (2E)-
CAS No.	619324-72-0
Molecular Formula	C23H26N2O3
Molecular Weight	378.47 g/mol
Synonyms	(2E)-3-[4-[[(2-Hydroxyethyl)[2-(1H-Indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenoic acid methyl ester; Methyl (2E)-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]acrylate; 2-Propenoic acid, 3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, methyl ester, (E)-; Acrylic acid indole derivative; N-[2-(1H-Indol-3-yl)ethyl]-N-(2-hydroxyethyl)-4-[(1E)-3-methoxy-3-oxo-1-propen-1-yl]benzenemethanamine
EINECS	Contact for details

Quality Control

Our production of 2-Propenoic Acid, 3-[4-[[(2-Hydroxyethyl)[2-(1H-Indol-3-Yl)Ethyl]Amino]Methyl]Phenyl]-, Methyl Ester, (2E)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting research and development grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, related substances, and residual solvents to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.