Description

3-(2,4-Dichloro-5-Fluorophenyl)-1-(3-Chlorophenyl)-1H-Pyrazole-5-Carboxylic Acid CAS NO 618382-96-0 is a high-purity, multi-halogenated pyrazole-carboxylic acid derivative serving as a critical advanced pharmaceutical intermediate. Its value lies in its complex halogenated aromatic structure, which is essential for synthesizing novel active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated chemical scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used in the production of Active Pharmaceutical Ingredients (APIs) for experimental and commercial pharmaceuticals.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, or insecticides, leveraging its halogenated pyrazole core.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Material Science: Potential intermediate for the synthesis of specialty polymers or organic electronic materials due to its aromatic and halogenated structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	3-(2,4-Dichloro-5-Fluorophenyl)-1-(3-Chlorophenyl)-1H-Pyrazole-5-Carboxylic Acid
CAS No.	618382-96-0
Molecular Formula	C16H8Cl3FN2O2
Molecular Weight	409.60 g/mol
Synonyms	3-(2,4-Dichloro-5-fluorophenyl)-1-(3-chlorophenyl)-1H-pyrazole-5-carboxylic acid; 1-(3-Chlorophenyl)-3-(2,4-dichloro-5-fluorophenyl)-1H-pyrazole-5-carboxylic acid; 5-Carboxy-1-(3-chlorophenyl)-3-(2,4-dichloro-5-fluorophenyl)pyrazole; Pyrazole-5-carboxylic acid, 3-(2,4-dichloro-5-fluorophenyl)-1-(3-chlorophenyl)-1H-; CAS 618382-96-0; 618382-96-0; Multi-halogenated pyrazole carboxylic acid intermediate
EINECS	Contact for details

Quality Control

Our production of 3-(2,4-Dichloro-5-Fluorophenyl)-1-(3-Chlorophenyl)-1H-Pyrazole-5-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and pharmaceutical applications. All materials undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.