Description

n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-[4-Hydroxy-6-(Trifluoromethyl)Pyrimidin-2-Yl]Guanidine is a high-value, multi-fluorinated guanidine derivative that serves as a critical synthetic intermediate in advanced chemical synthesis. Its complex structure, featuring multiple trifluoromethyl groups, imparts unique electronic and steric properties essential for developing specialized agrochemicals and pharmaceuticals. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical and life science industries for creating novel active ingredients.

Application

• Agrochemical Intermediate: Key building block for the synthesis of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Pharmaceutical Research: Used in medicinal chemistry as a privileged scaffold for developing drug candidates, particularly in areas targeting enzymes and receptors where strong hydrogen-bonding motifs are required.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced materials with specific fluorinated properties.
• Chemical Biology Probe: Utilized in the development of molecular probes and inhibitors to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the agrochemical and pharmaceutical sectors.

Basic Information

Product Name	n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-[4-Hydroxy-6-(Trifluoromethyl)Pyrimidin-2-Yl]Guanidine
CAS No.	618092-26-5
Molecular Formula	C15H8F9N5O
Molecular Weight	447.25 g/mol
Synonyms	2-[[[3,5-Bis(trifluoromethyl)phenyl]amino][imino]methyl]amino-4-hydroxy-6-(trifluoromethyl)pyrimidine; 1-[3,5-Bis(trifluoromethyl)phenyl]-3-[4-hydroxy-6-(trifluoromethyl)pyrimidin-2-yl]guanidine; N-(3,5-Bis(trifluoromethyl)phenyl)-N'-[4-hydroxy-6-(trifluoromethyl)pyrimidin-2-yl]guanidine; 618092-26-5; Guanidine, N-[3,5-bis(trifluoromethyl)phenyl]-N'-[4-hydroxy-6-(trifluoromethyl)-2-pyrimidinyl]-
EINECS	Contact for details

Quality Control

Every batch of n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-[4-Hydroxy-6-(Trifluoromethyl)Pyrimidin-2-Yl]Guanidine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.