Description

2H-Pyran-5-Carboxamide,6-(Difluoromethyl)-3,4-Dihydro-n-3-Thienyl-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new drug candidates, especially those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Research: Serves as a structural motif in the development of new-generation pesticides and herbicides with specific modes of action.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme interactions and biological pathways due to its unique fused pyran-thiophene scaffold.
• Material Science Applications: Potential building block for creating novel organic electronic materials or ligands for catalytic systems.
• Process Chemistry & Scale-Up: Supplied to contract development and manufacturing organizations (CDMOs) for process optimization and cGMP production campaigns.

Basic Information

Product Name	2H-Pyran-5-Carboxamide,6-(Difluoromethyl)-3,4-Dihydro-n-3-Thienyl-(9Ci)
CAS No.	616204-53-6
Molecular Formula	C11H11F2NO2S
Molecular Weight	259.27 g/mol
Synonyms	6-(Difluoromethyl)-3,4-dihydro-N-3-thienyl-2H-pyran-5-carboxamide; 6-(Difluoromethyl)-N-(thiophen-3-yl)-3,4-dihydro-2H-pyran-5-carboxamide; 3,4-Dihydro-6-(difluoromethyl)-N-3-thienyl-2H-pyran-5-carboxamide; 616204-53-6; 2H-Pyran-5-carboxamide, 6-(difluoromethyl)-3,4-dihydro-N-3-thienyl-; N-(Thiophen-3-yl)-6-(difluoromethyl)-3,4-dihydro-2H-pyran-5-carboxamide
EINECS	Contact for details

Quality Control

Our 2H-Pyran-5-Carboxamide,6-(Difluoromethyl)-3,4-Dihydro-n-3-Thienyl-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP guidelines for advanced intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.