Description

L-β-Homo-Tyr-Oh.Hcl is a non-natural amino acid derivative, specifically a homologated tyrosine analog, with the CAS number 615537-19-4. This compound is a critical building block in advanced pharmaceutical research and peptide synthesis, valued for its ability to modulate peptide structure, stability, and biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce structural modifications that enhance metabolic stability or receptor binding affinity.
• Biochemical Research: Serves as a tool compound for studying enzyme-substrate interactions, receptor-ligand binding, and structure-activity relationships (SAR) in medicinal chemistry.
• Peptidomimetic Design: Incorporated into peptidomimetic scaffolds to create drug candidates with improved pharmacokinetic properties over natural peptides.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	L-β-Homo-Tyr-Oh.Hcl
CAS No.	615537-19-4
Molecular Formula	C11H15NO4 • HCl
Molecular Weight	261.70 g/mol (Free base: 225.24 g/mol)
Synonyms	L-β-Homotyrosine hydrochloride; (S)-2-Amino-4-(4-hydroxyphenyl)butanoic acid hydrochloride; H-Homotyrosine-OH•HCl; β-Homo-L-tyrosine HCl; 4-[(2S)-2-Amino-4-hydroxybutyl]phenol hydrochloride; L-β-Homo-Tyr-OH•HCl; (S)-2-Amino-4-(4-hydroxyphenyl)butyric acid hydrochloride
EINECS	Contact for details

Quality Control

Our L-β-Homo-Tyr-Oh.Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure the material meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.