Description

2H,6H,8H-Difuro[3,2-B:3,4-C]Furan-6-One, Tetrahydro-3,5-Dihydroxy-5-Methyl-, (3R,3As,5R,5As,8Ar)- (9Ci) is a complex, stereochemically defined furanone derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the construction of intricate molecular architectures with precise three-dimensional control. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for complex natural product analogs and targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the defined spatial arrangement is crucial for biological activity.
• Organic Synthesis Research: Acts as a versatile precursor for constructing fused polycyclic ether and lactone frameworks in academic and industrial R&D settings.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high-purity, complex heterocyclic cores.
• Material Science Precursor: Potential use in developing novel organic electronic materials or ligands for asymmetric catalysis.

Basic Information

Product Name	2H,6H,8H-Difuro[3,2-B:3,4-C]Furan-6-One, Tetrahydro-3,5-Dihydroxy-5-Methyl-, (3R,3As,5R,5As,8Ar)- (9Ci)
CAS No.	615265-09-3
Molecular Formula	C11H14O6
Molecular Weight	242.23 g/mol
Synonyms	(3R,3aS,5R,5aS,8aR)-Tetrahydro-3,5-dihydroxy-5-methyl-2H,6H,8H-difuro[3,2-b:3',4'-c]furan-6-one; 5-Methyl-3,5-dihydroxy-tetrahydro-difuro[3,2-b:3,4-c]furan-6-one (stereoisomer); Difuro[3,2-b:3,4-c]furan-6-one derivative; Chiral Furanone Building Block; CAS 615265-09-3; (3R,3aS,5R,5aS,8aR)-Isomer of the specified difurofuranone.
EINECS	Contact for details

Quality Control

We supply this advanced intermediate under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Our standard offering is characterized by HPLC purity ≥95% (area percentage), with specifications for chiral purity and key impurities available. A comprehensive Certificate of Analysis (COA) detailing identity (IR, NMR), assay, chiral purity, and related substances is provided with each shipment. Specifications can be customized to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.