Description

1-Benzyloxy-4-Bromo-2-Iodo-Benzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic positioning of halogen atoms, which serve as versatile handles for subsequent cross-coupling reactions and functional group transformations. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for the development of complex molecules and novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring complex biaryl or heteroaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where specific halogenated aromatic cores are required for bioactivity.
• Material Science Research: Acts as a monomer or building block for creating specialized polymers, liquid crystals, or organic electronic materials.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed reactions such as Suzuki, Negishi, and Stille couplings, enabling the formation of carbon-carbon bonds.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for metal catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and target identification.

Basic Information

Product Name	1-Benzyloxy-4-Bromo-2-Iodo-Benzene
CAS No.	612833-66-6
Molecular Formula	C₁₃H₁₀BrIO
Molecular Weight	389.03 g/mol
Synonyms	4-Bromo-2-iodo-1-(phenylmethoxy)benzene; 1-Benzyloxy-4-bromo-2-iodobenzene; 4-Bromo-2-iodophenyl benzyl ether; Benzene, 1-(benzyloxy)-4-bromo-2-iodo-; 2-Iodo-4-bromophenyl benzyl ether
EINECS	Contact for details

Quality Control

Our 1-Benzyloxy-4-Bromo-2-Iodo-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.