Description

tert-Butyl 4-((4-Chloro-7-Methoxyquinazolin-6-Yl)Oxy)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of targeted therapeutic agents. This compound is critical for research and development in medicinal chemistry, offering a key building block with precise molecular architecture. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the development of novel small-molecule drugs, particularly kinase inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted anticancer agents and kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a critical synthon in the manufacturing process of final drug substances.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and process development projects.
• Academic Research: Employed in university and institutional labs for biochemical and pharmacological studies.

Basic Information

Product Name	tert-Butyl 4-((4-Chloro-7-Methoxyquinazolin-6-Yl)Oxy)Piperidine-1-Carboxylate
CAS No.	612501-45-8
Molecular Formula	C19H24ClN3O4
Molecular Weight	393.86 g/mol
Synonyms	1-Boc-4-((4-chloro-7-methoxyquinazolin-6-yl)oxy)piperidine; 1-(tert-Butoxycarbonyl)-4-[(4-chloro-7-methoxy-6-quinazolinyl)oxy]piperidine; tert-Butyl 4-[(4-chloro-7-methoxy-6-quinazolinyl)oxy]-1-piperidinecarboxylate; 4-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)piperidine-1-carboxylic acid tert-butyl ester; BOC-Piperidine Quinazoline Intermediate; CAS 612501-45-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-((4-Chloro-7-Methoxyquinazolin-6-Yl)Oxy)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.