Description

8-Benzenesulfonyl-6-(4-Nitrophenylamino)-2,3-Dihydro-1H-Indolizin-5-One is a specialized heterocyclic organic compound featuring a unique indolizinone core functionalized with benzenesulfonyl and nitrophenylamino groups. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by research institutions and pharmaceutical R&D departments engaged in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and library synthesis.
• Biochemical Tool Compound: May be employed in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Organic Synthesis: Acts as a versatile substrate for further chemical modifications, such as cross-coupling or reduction reactions, due to its reactive functional groups.
• Academic Research: Utilized in universities and research institutes for projects involving heterocyclic chemistry and novel synthetic methodologies.

Basic Information

Product Name	8-Benzenesulfonyl-6-(4-Nitrophenylamino)-2,3-Dihydro-1H-Indolizin-5-One
CAS No.	612065-26-6
Molecular Formula	C21H17N3O4S
Molecular Weight	407.44 g/mol
Synonyms	6-[(4-Nitrophenyl)amino]-8-(phenylsulfonyl)-2,3-dihydro-1H-indolizin-5-one; 8-(Phenylsulfonyl)-6-[(4-nitrophenyl)amino]-2,3-dihydro-5H-indolizin-5-one; 8-Benzenesulfonyl-6-(4-nitroanilino)-2,3-dihydro-1H-indolizin-5-one; CAS 612065-26-6
EINECS	Contact for details

Quality Control

Our high-purity 8-Benzenesulfonyl-6-(4-Nitrophenylamino)-2,3-Dihydro-1H-Indolizin-5-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.