Description

2-(Trifluoromethyl)Quinolin-5-Amine is a high-value, fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a quinoline scaffold and a trifluoromethyl group, makes it indispensable for creating compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for targets in oncology, CNS disorders, and infectious diseases.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides where the trifluoromethyl group can improve lipophilicity and metabolic stability.
• Material Science: Building block for creating specialty chemicals, including dyes, pigments, and organic electronic materials.
• Chemical Biology: Useful as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies due to its distinct fluorine signature.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and novel heterocyclic chemistry research.

Basic Information

Product Name	2-(Trifluoromethyl)Quinolin-5-Amine
CAS No.	611231-26-6
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	5-Amino-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-5-quinolinamine; 5-Quinolinamine, 2-(trifluoromethyl)-; Quinolin-5-amine, 2-(trifluoromethyl)-; 2-Trifluoromethylquinolin-5-ylamine
EINECS	Contact for details

Quality Control

Every batch of 2-(Trifluoromethyl)Quinolin-5-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.