Description

Quinoline, 1,2,3,4-Tetrahydro-2-(1-Methylethyl)-, (2S)- (9Ci) is a chiral, saturated quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking high-purity, stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used in the development and synthesis of chiral ligands for asymmetric hydrogenation and other catalytic transformations.
• Agrochemical Synthesis: Serves as an intermediate in the production of advanced, stereoselective pesticides and herbicides.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial Research: A valuable compound for methodological development in organic chemistry and medicinal chemistry research programs.
• Material Science: Potential use as a precursor for chiral organic frameworks or functional materials.

Basic Information

Product Name	Quinoline, 1,2,3,4-Tetrahydro-2-(1-Methylethyl)-, (2S)- (9Ci)
CAS No.	608525-30-0
Molecular Formula	C13H17N
Molecular Weight	187.28 g/mol
Synonyms	(2S)-2-Isopropyl-1,2,3,4-tetrahydroquinoline; (S)-2-Isopropyl-1,2,3,4-tetrahydroquinoline; L-2-Isopropyl-1,2,3,4-tetrahydroquinoline; (-)-2-Isopropyl-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-2-(1-methylethyl)quinoline, (2S)-; (S)-2-Isopropyl-1,2,3,4-tetrahydroquinoline; Tetrahydroquinoline derivative
EINECS	Contact for details

Quality Control

Our Quinoline, 1,2,3,4-Tetrahydro-2-(1-Methylethyl)-, (2S)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination (HPLC, optical rotation), to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.