Description

4-Bromo-8-Iodoquinoline is a high-purity, halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of organic semiconductors and light-emitting materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of both bromo and iodo substituents.
• Ligand Synthesis: Employed in the preparation of novel nitrogen-containing ligands for catalysis.
• Chemical Biology: Used as a probe or tag in bioconjugation and target identification studies.

Basic Information

Product Name	4-Bromo-8-Iodoquinoline
CAS No.	608143-12-0
Molecular Formula	C9H5BrIN
Molecular Weight	333.96 g/mol
Synonyms	8-Iodo-4-bromoquinoline; Quinoline, 4-bromo-8-iodo-; 4-Bromo-8-iodoquinoline; 608143-12-0
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-8-Iodoquinoline is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency to meet the rigorous demands of research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.