Description

4-[3-(6-Methyl-2-Pyridinyl)-1H-Pyrazol-4-Yl]-Quinoline CAS NO 607737-87-1 is a high-purity, heterocyclic organic compound featuring a quinoline core linked to a substituted pyrazolyl-pyridinyl moiety. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and for probing structure-activity relationships.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries to screen for biological activity and optimize drug-like properties.
• Kinase Inhibitor Development: The structural motif is commonly associated with molecules designed to modulate kinase enzymes, a major target class in modern drug discovery.
• Chemical Biology Probes: Used in academic and industrial research to study specific biological pathways and protein functions.
• Process Chemistry & Scale-Up: Supplied to support the development of robust, scalable synthetic routes from laboratory to pilot plant scale.
• Reference Standard: High-purity grades are suitable for use as an analytical standard for quality control and method development.

Basic Information

Product Name	4-[3-(6-Methyl-2-Pyridinyl)-1H-Pyrazol-4-Yl]-Quinoline
CAS No.	607737-87-1
Molecular Formula	C₁₈H₁₄N₄
Molecular Weight	286.33 g/mol
Synonyms	4-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)quinoline; Quinoline, 4-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-; 4-(3-(6-Methyl-2-pyridyl)-1H-pyrazol-4-yl)quinoline; 607737-87-1; 4-[3-(6-Methyl-2-pyridyl)-1H-pyrazol-4-yl]quinoline
EINECS	Contact for details

Quality Control

Every batch of 4-[3-(6-Methyl-2-Pyridinyl)-1H-Pyrazol-4-Yl]-Quinoline is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) providing detailed results for identity, purity, and impurity profiles are available upon request. We support cGMP compliance for advanced intermediates intended for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.