Description

Acetamide, 2-[[2-(4-Fluorophenyl)-6-Methyl-4-Quinazolinyl]Thio]-n-Propyl- (9Ci) is a specialized organic compound featuring a quinazoline core, a fluorophenyl group, and a thioether-linked propylacetamide side chain. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel therapeutic agents, particularly in oncology and targeted disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Oncology Drug Development: A key precursor in the research of targeted therapies due to its quinazoline-based structure.
• Biochemical Tool Compound: Employed in biochemical assays to study specific enzyme interactions and signaling pathways.
• Fine Chemical Synthesis: Used in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.

Basic Information

Product Name	Acetamide, 2-[[2-(4-Fluorophenyl)-6-Methyl-4-Quinazolinyl]Thio]-n-Propyl- (9Ci)
CAS No.	606132-84-7
Molecular Formula	C20H20FN3OS
Molecular Weight	369.46 g/mol
Synonyms	2-[[2-(4-Fluorophenyl)-6-methyl-4-quinazolinyl]thio]-N-propylacetamide; N-Propyl-2-((2-(4-fluorophenyl)-6-methylquinazolin-4-yl)thio)acetamide; 2-((2-(4-Fluorophenyl)-6-methylquinazolin-4-yl)thio)-N-propylacetamide; Acetamide, 2-((2-(4-fluorophenyl)-6-methyl-4-quinazolinyl)thio)-N-propyl-; CAS 606132-84-7
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.