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Acetamide, n-Cyclopropyl-2-[[2-(4-Fluorophenyl)-7-Methyl-4-Quinazolinyl]Thio]- (9Ci) CAS NO 606132-73-4
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CAS No.:606132-73-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Acetamide, n-Cyclopropyl-2-[[2-(4-Fluorophenyl)-7-Methyl-4-Quinazolinyl]Thio]- (9Ci) is a high-purity, synthetic organic compound belonging to the quinazoline class, designed for advanced research and development. This specialized chemical serves as a critical pharmacological reference standard and a key synthetic intermediate in the creation of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on oncology, kinase inhibition, and targeted drug discovery.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of novel quinazoline-based drug candidates targeting specific kinases.
- Biochemical Research: Used as a reference compound in enzyme inhibition assays and structure-activity relationship (SAR) studies.
- Reference Standard: Serves as a certified analytical standard for quality control and method validation in pharmaceutical analysis.
- Drug Discovery: Employed in high-throughput screening (HTS) libraries to identify potential lead compounds for therapeutic development.
- Academic Research: Utilized in university and institutional labs for investigating new chemical entities and their biological pathways.
- Preclinical Development: Supports the synthesis of compounds for in vitro and in vivo pharmacological evaluation.
Basic Information
| Product Name | Acetamide, n-Cyclopropyl-2-[[2-(4-Fluorophenyl)-7-Methyl-4-Quinazolinyl]Thio]- (9Ci) |
| CAS No. | 606132-73-4 |
| Molecular Formula | C21H18FN3OS |
| Molecular Weight | 379.45 g/mol |
| Synonyms | N-Cyclopropyl-2-((2-(4-fluorophenyl)-7-methylquinazolin-4-yl)thio)acetamide; 2-[[2-(4-Fluorophenyl)-7-methyl-4-quinazolinyl]thio]-N-cyclopropylacetamide; 606132-73-4; Quinazoline thioacetamide derivative; 4-Quinazolinyl thioacetamide; Kinase inhibitor intermediate; Fluorophenyl quinazoline derivative |
| EINECS | Contact for details |
Quality Control
Our production of Acetamide, n-Cyclopropyl-2-[[2-(4-Fluorophenyl)-7-Methyl-4-Quinazolinyl]Thio]- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization using HPLC, NMR, and mass spectrometry to ensure structural identity and high purity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, impurities, and batch-specific data to support your regulatory and research requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Single Unknown Impurity (HPLC) | ≤ 1.0% |
| Total Impurities (HPLC) | ≤ 3.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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