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Acetamide, n-Cyclopropyl-2-[[2-(4-Fluorophenyl)-7-Methyl-4-Quinazolinyl]Thio]- (9Ci) CAS NO 606132-73-4


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CAS No.:606132-73-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Acetamide, n-Cyclopropyl-2-[[2-(4-Fluorophenyl)-7-Methyl-4-Quinazolinyl]Thio]- (9Ci) is a high-purity, synthetic organic compound belonging to the quinazoline class, designed for advanced research and development. This specialized chemical serves as a critical pharmacological reference standard and a key synthetic intermediate in the creation of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on oncology, kinase inhibition, and targeted drug discovery.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel quinazoline-based drug candidates targeting specific kinases.
  • Biochemical Research: Used as a reference compound in enzyme inhibition assays and structure-activity relationship (SAR) studies.
  • Reference Standard: Serves as a certified analytical standard for quality control and method validation in pharmaceutical analysis.
  • Drug Discovery: Employed in high-throughput screening (HTS) libraries to identify potential lead compounds for therapeutic development.
  • Academic Research: Utilized in university and institutional labs for investigating new chemical entities and their biological pathways.
  • Preclinical Development: Supports the synthesis of compounds for in vitro and in vivo pharmacological evaluation.

Basic Information

Product Name Acetamide, n-Cyclopropyl-2-[[2-(4-Fluorophenyl)-7-Methyl-4-Quinazolinyl]Thio]- (9Ci)
CAS No. 606132-73-4
Molecular Formula C21H18FN3OS
Molecular Weight 379.45 g/mol
Synonyms N-Cyclopropyl-2-((2-(4-fluorophenyl)-7-methylquinazolin-4-yl)thio)acetamide; 2-[[2-(4-Fluorophenyl)-7-methyl-4-quinazolinyl]thio]-N-cyclopropylacetamide; 606132-73-4; Quinazoline thioacetamide derivative; 4-Quinazolinyl thioacetamide; Kinase inhibitor intermediate; Fluorophenyl quinazoline derivative
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Quality Control

Our production of Acetamide, n-Cyclopropyl-2-[[2-(4-Fluorophenyl)-7-Methyl-4-Quinazolinyl]Thio]- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization using HPLC, NMR, and mass spectrometry to ensure structural identity and high purity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, impurities, and batch-specific data to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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