Description

Acetamide, 2-[[2-(4-Fluorophenyl)-8-Methyl-4-Quinazolinyl]Thio]-N,n-Dimethyl- (9Ci) is a high-purity, synthetic organic compound belonging to the quinazoline class, designed for advanced research and development applications. This specialized chemical serves as a critical building block or intermediate in the synthesis of novel pharmaceutical candidates, particularly those targeting specific enzymatic pathways. It is essential for medicinal chemistry researchers and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for drug discovery programs. The compound's unique structure offers a valuable scaffold for exploring new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors or other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Biochemical Assay Development: Employed as a reference standard or probe molecule in high-throughput screening (HTS) campaigns to identify potential drug candidates.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization studies for the efficient, scalable synthesis of complex drug molecules.
• Academic Research: Provides a valuable tool for universities and research institutes studying heterocyclic chemistry, organic synthesis methodologies, and drug discovery mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry's outsourced R&D and production needs.

Basic Information

Product Name	Acetamide, 2-[[2-(4-Fluorophenyl)-8-Methyl-4-Quinazolinyl]Thio]-N,n-Dimethyl- (9Ci)
CAS No.	606131-66-2
Molecular Formula	C19H18FN3OS
Molecular Weight	355.43 g/mol
Synonyms	2-[[2-(4-Fluorophenyl)-8-methyl-4-quinazolinyl]thio]-N,N-dimethylacetamide; N,N-Dimethyl-2-((2-(4-fluorophenyl)-8-methylquinazolin-4-yl)thio)acetamide; 2-((2-(4-Fluorophenyl)-8-methylquinazolin-4-yl)thio)-N,N-dimethylacetamide; Acetamide, 2-((2-(4-fluorophenyl)-8-methyl-4-quinazolinyl)thio)-N,N-dimethyl-; CAS 606131-66-2
EINECS	Contact for details

Quality Control

Every batch of Acetamide, 2-[[2-(4-Fluorophenyl)-8-Methyl-4-Quinazolinyl]Thio]-N,n-Dimethyl- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, which is critical for research reproducibility and process development. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and mass spectrometry is supplied with each shipment. Our quality commitment aligns with the standards expected for pharmaceutical research intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.