Description

Acetamide, 2-[[8-Ethyl-2-(4-Fluorophenyl)-4-Quinazolinyl]Thio]-n-Propyl- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in modern medicinal chemistry for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel quinazoline-based drug candidates.
• Kinase Inhibitor Research: Used in the development and screening of potential kinase inhibitors for oncology and other therapeutic areas.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Preclinical Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	Acetamide, 2-[[8-Ethyl-2-(4-Fluorophenyl)-4-Quinazolinyl]Thio]-n-Propyl- (9Ci)
CAS No.	606131-29-7
Molecular Formula	C21H22FN3OS
Molecular Weight	383.48 g/mol
Synonyms	2-[[8-Ethyl-2-(4-fluorophenyl)-4-quinazolinyl]thio]-N-propylacetamide; N-Propyl-2-((8-ethyl-2-(4-fluorophenyl)quinazolin-4-yl)thio)acetamide; 2-(((8-Ethyl-2-(4-fluorophenyl)quinazolin-4-yl)thio))-N-propylacetamide; Acetamide, 2-(((8-ethyl-2-(4-fluorophenyl)-4-quinazolinyl)thio))-N-propyl-; CAS 606131-29-7
EINECS	Contact for details

Quality Control

Our Acetamide, 2-[[8-Ethyl-2-(4-Fluorophenyl)-4-Quinazolinyl]Thio]-n-Propyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.