Description

Quinoline, 1-[[(1,4-Dihydro-5,6-Dimethyl-4-Oxothieno[2,3-D]Pyrimidin-2-Yl)Thio]Acetyl]-1,2,3,4-Tetrahydro- (9Ci) is a sophisticated heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate (API intermediate) and a valuable scaffold in medicinal chemistry research. Its complex molecular architecture, featuring fused quinoline and thienopyrimidinone rings, makes it a key building block for the synthesis of novel bioactive molecules. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: May be employed in biochemical assays to study enzyme inhibition or receptor modulation.
• Organic Synthesis Building Block: Utilized in advanced organic synthesis for constructing complex polyheterocyclic systems.
• Agrochemical Research: Investigated as an intermediate for developing novel crop protection agents with specific biological activity.

Basic Information

Item	Details
Product Name	Quinoline, 1-[[(1,4-Dihydro-5,6-Dimethyl-4-Oxothieno[2,3-D]Pyrimidin-2-Yl)Thio]Acetyl]-1,2,3,4-Tetrahydro- (9Ci)
CAS No.	606107-72-6
Molecular Formula	C21H21N3O2S2
Molecular Weight	411.54 g/mol
Synonyms	1-[[(1,4-Dihydro-5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-2-yl)thio]acetyl]-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-1-[[2-[(5,6-dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)thio]acetyl]]quinoline; CAS 606107-72-6; Thienopyrimidine-quinoline conjugate; Tetrahydroquinoline thioacetate derivative.
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. For cGMP-grade material or material intended for non-clinical safety studies, specific quality agreements and documentation can be established.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.