Description

2-Thiophenecarboxamide,n-[2-[(3-Cyano-8-Methyl-2-Quinolinyl)Amino]Ethyl]-(9Ci) is a sophisticated heterocyclic organic compound featuring a quinoline core linked to a thiophene carboxamide moiety via an ethylamino spacer. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Acts as a building block for creating new active ingredients in crop protection and pest management solutions.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological processes and target validation.
• Organic Synthesis: Utilized in advanced organic synthesis for constructing complex heterocyclic systems with potential biological activity.

Basic Information

Product Name	2-Thiophenecarboxamide,n-[2-[(3-Cyano-8-Methyl-2-Quinolinyl)Amino]Ethyl]-(9Ci)
CAS No.	606105-08-2
Molecular Formula	C₁₈H₁₆N₄OS
Molecular Weight	336.41 g/mol
Synonyms	N-[2-[(3-Cyano-8-methyl-2-quinolinyl)amino]ethyl]-2-thiophenecarboxamide; 2-Quinolinecarboxamide, N-[2-[(3-cyano-8-methyl-2-quinolinyl)amino]ethyl]thienyl-; 606105-08-2; 8-Methyl-N-(2-((3-cyano-8-methylquinolin-2-yl)amino)ethyl)thiophene-2-carboxamide; (9CI) designation intermediate; Thiophene-quinoline hybrid amide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet the specific requirements of your R&D or cGMP development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.