Description

5H-1,2,4-Triazino[5,6-B]Indole,3-(Ethylthio)-8-Fluoro-5-Methyl-(9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused triazinoindole structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, or anti-infective applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the biological activity of triazinoindole derivatives and optimize lead compounds.
• Active Pharmaceutical Ingredient (API) Development: A crucial precursor in the multi-step synthesis of complex APIs, leveraging its fluorine and sulfur-containing functional groups for specific pharmacological properties.
• Biochemical Research: May be utilized as a reference standard or probe in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities for clinical trials.

Basic Information

Product Name	5H-1,2,4-Triazino[5,6-B]Indole,3-(Ethylthio)-8-Fluoro-5-Methyl-(9Ci)
CAS No.	603948-08-9
Molecular Formula	C12H11FN4S
Molecular Weight	262.31 g/mol
Synonyms	3-(Ethylthio)-8-fluoro-5-methyl-5H-[1,2,4]triazino[5,6-b]indole; 8-Fluoro-5-methyl-3-(ethylthio)-5H-[1,2,4]triazino[5,6-b]indole; 5H-[1,2,4]Triazino[5,6-b]indole, 3-(ethylthio)-8-fluoro-5-methyl-; 603948-08-9; 3-Ethylsulfanyl-8-fluoro-5-methyl-5H-[1,2,4]triazino[5,6-b]indole
EINECS	Contact for details

Quality Control

Our production of 5H-1,2,4-Triazino[5,6-B]Indole,3-(Ethylthio)-8-Fluoro-5-Methyl-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements, as applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound should be handled as a moisture-sensitive material. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.