Description

Acetamide, 2-[(8-Bromo-5-Methyl-5H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]-n-Cyclopropyl- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating bromo, triazinoindole, and cyclopropyl moieties. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Oncology Drug Development: Employed in the construction of potential kinase inhibitors or other targeted cancer therapies.
• CNS-Active Compound Synthesis: Serves as a scaffold for developing molecules intended to cross the blood-brain barrier.
• Biochemical Probe Development: Utilized to create tool compounds for investigating enzyme function or receptor interactions in biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Used in university and institutional labs for cutting-edge chemical biology and drug discovery programs.

Basic Information

Product Name	Acetamide, 2-[(8-Bromo-5-Methyl-5H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]-n-Cyclopropyl- (9Ci)
CAS No.	603947-08-6
Molecular Formula	C15H14BrN5OS
Molecular Weight	392.27 g/mol
Synonyms	N-Cyclopropyl-2-[(8-bromo-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]acetamide; 2-[(8-Bromo-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]-N-cyclopropylacetamide; 603947-08-6; Acetamide, 2-[(8-bromo-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]-N-cyclopropyl-; N-Cyclopropyl-2-((8-bromo-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)acetamide
EINECS	Contact for details

Quality Control

Our Acetamide, 2-[(8-Bromo-5-Methyl-5H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]-n-Cyclopropyl- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements for research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; handling under an inert atmosphere is recommended for long-term storage to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.