Description

(S)-(+)-Quinuclidin-3-Ol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its defined stereochemistry and quinuclidine core structure make it a valuable synthon for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise molecular control.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of muscarinic receptor antagonists and other therapeutic agents.
• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in catalytic reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Agrochemical Development: Serves as a building block for novel crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways.
• Fine Chemical Synthesis: Integral component in multi-step syntheses of complex, high-value organic molecules.

Basic Information

Product Name	(S)-(+)-Quinuclidin-3-Ol Hydrochloride
CAS No.	603126-48-3
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	(3S)-Quinuclidin-3-ol hydrochloride; (S)-3-Quinuclidinol hydrochloride; (+)-3-Quinuclidinol hydrochloride; (S)-(+)-3-Hydroxyquinuclidine hydrochloride; 1-Azabicyclo[2.2.2]octan-3-ol, (3S)-, hydrochloride; (S)-Quinuclidinol HCl; (S)-1-Azabicyclo[2.2.2]octan-3-ol hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-(+)-Quinuclidin-3-Ol Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.