Description

Benzo[B]Thiophene-4-Ol, 4,5,6,7-Tetrahydro-, (-)- (9Ci) is a chiral, saturated benzothiophene derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel pharmaceuticals and agrochemicals. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, asymmetric synthesis, and the creation of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the development of novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in transition metal catalysis.
• Material Science Research: Investigated as a monomer or functional component in the synthesis of advanced organic electronic materials and liquid crystals.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for constructing complex heterocyclic frameworks.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	Benzo[B]Thiophene-4-Ol, 4,5,6,7-Tetrahydro-, (-)- (9Ci)
CAS No.	601525-52-4
Molecular Formula	C8H10OS
Molecular Weight	154.23 g/mol
Synonyms	(-)-4,5,6,7-Tetrahydrobenzo[b]thiophen-4-ol; (4S)-4,5,6,7-Tetrahydro-1-benzothiophen-4-ol; 4,5,6,7-Tetrahydrobenzo[b]thiophen-4-ol, (-)-; 4-Hydroxy-4,5,6,7-tetrahydrobenzo[b]thiophene; 4,5,6,7-Tetrahydro-1-benzothiophene-4-ol; Tetrahydrobenzothiophen-4-ol
EINECS	Contact for details

Quality Control

Our production of Benzo[B]Thiophene-4-Ol, 4,5,6,7-Tetrahydro-, (-)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); containers should be kept tightly sealed under an inert atmosphere for long-term storage to prevent oxidation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.