Description

2-Benzyl-5-Bromo-1,2,3,4-Tetrahydro-2,6-Naphthyridine is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 601514-63-0. This compound is a critical building block in modern medicinal chemistry, valued for its unique fused heterocyclic structure which serves as a versatile scaffold for drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a privileged scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Used in the research and synthesis of potential therapeutics for neurological disorders.
• Oncology Research: Employed as a building block for creating small molecule inhibitors and targeted cancer therapies.
• Chemical Biology: Utilized as a probe or tool compound for studying biological processes and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-Benzyl-5-Bromo-1,2,3,4-Tetrahydro-2,6-Naphthyridine
CAS No.	601514-63-0
Molecular Formula	C₁₅H₁₅BrN₂
Molecular Weight	303.20 g/mol
Synonyms	5-Bromo-2-benzyl-1,2,3,4-tetrahydro-2,6-naphthyridine; 2,6-Naphthyridine, 5-bromo-1,2,3,4-tetrahydro-2-(phenylmethyl)-; 2-Benzyl-5-bromo-1,2,3,4-tetrahydro-2,6-naphthyridine; 5-Bromo-2-benzyl-1,2,3,4-tetrahydro-2,6-naphthyridine; 601514-63-0; 2-Benzyl-5-bromo-1,2,3,4-tetrahydro-2,6-naphthyridine; Tetrahydro-2,6-naphthyridine derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for all critical parameters are available upon request. Our quality management system supports development under cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.