Description

4(3H)-Quinazolinone, 2-Chloro-5-Cyclopropyl-7-Methoxy- is a high-purity, advanced pharmaceutical intermediate characterized by its distinct quinazolinone core structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in oncology and anti-infective research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel quinazolinone-based drug candidates.
• Oncology Research: Used in the synthesis of small molecule inhibitors targeting specific kinases and enzymes involved in cancer cell proliferation.
• Anti-infective Agent Development: Serves as a core scaffold for creating new antimicrobial and antiviral compounds.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag to study protein-ligand interactions and enzyme functions.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization for pharmaceutical clients.
• Academic Research: Utilized in university and institutional labs for heterocyclic chemistry studies and the exploration of new synthetic methodologies.

Basic Information

Product Name	4(3H)-Quinazolinone, 2-Chloro-5-Cyclopropyl-7-Methoxy-
CAS No.	601514-53-8
Molecular Formula	C₁₂H₁₁ClN₂O₂
Molecular Weight	250.68 g/mol
Synonyms	2-Chloro-5-cyclopropyl-7-methoxyquinazolin-4(3H)-one; 2-Chloro-5-cyclopropyl-7-methoxy-4(3H)-quinazolinone; 5-Cyclopropyl-2-chloro-7-methoxy-4(3H)-quinazolinone; 7-Methoxy-2-chloro-5-cyclopropyl-3H-quinazolin-4-one; 2-Chloro-7-methoxy-5-cyclopropyl-4-quinazolinol; 601514-53-8; Quinazolinone derivative CPQ-M
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone, 2-Chloro-5-Cyclopropyl-7-Methoxy- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates for preclinical and clinical-stage development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.