Description

3-(8-Chloroquinoline-4-Yl)Acrylic Acid is a high-value, functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a chloroquinoline moiety and an acrylic acid group, makes it an essential intermediate for creating complex molecules with targeted properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for anti-malarial, anti-inflammatory, or anti-cancer research applications.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the quinoline scaffold imparts specific biological activity.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Ligand and Catalyst Development: Serves as a backbone for synthesizing novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Fluorescent Probe and Dye Intermediate: Utilized in the design of quinoline-based fluorescent markers and dyes for analytical and diagnostic applications.
• Academic and R&D Laboratories: Employed in fundamental chemical research for studying structure-activity relationships and novel reaction pathways.

Basic Information

Product Name	3-(8-Chloroquinoline-4-Yl)Acrylic Acid
CAS No.	69976-08-5
Molecular Formula	C₁₂H₈ClNO₂
Molecular Weight	233.65 g/mol
Synonyms	(E)-3-(8-Chloroquinolin-4-yl)acrylic acid; 3-(8-Chloro-4-quinolyl)acrylic acid; 8-Chloro-4-quinolineacrylic acid; 4-Quinolineacrylic acid, 8-chloro-; trans-3-(8-Chloroquinolin-4-yl)acrylic acid; 69976-08-5; 3-(8-Chloro-4-quinolyl)-2-propenoic acid
EINECS	Contact for details

Quality Control

Every batch of 3-(8-Chloroquinoline-4-Yl)Acrylic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.