Description

(2-Chloro-4-Fluorophenyl)Phenylmethanone is a high-purity diaryl ketone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique halogenated aromatic structure, which provides versatile reactivity for constructing complex molecular frameworks. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine and chlorine substituents for enhanced bioactivity and stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: A versatile electrophile in Friedel-Crafts acylation and Suzuki-Miyaura cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new reaction pathways in medicinal chemistry.

Basic Information

Product Name	(2-Chloro-4-Fluorophenyl)Phenylmethanone
CAS No.	69943-47-1
Molecular Formula	C13H8ClFO
Molecular Weight	234.65 g/mol
Synonyms	2-Chloro-4-fluorobenzophenone; (2-Chloro-4-fluorophenyl)(phenyl)methanone; Benzophenone, 2-chloro-4'-fluoro-; 4-Fluoro-2-chlorobenzophenone; 2-Chloro-4-fluorobenzophenone; Phenyl 2-chloro-4-fluorophenyl ketone; 2-Chloro-4'-fluorobenzophenone; 69943-47-1
EINECS	Contact for details

Quality Control

Our production of (2-Chloro-4-Fluorophenyl)Phenylmethanone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.